Developmental Activation of Calmodulin-Dependent Facilitation of Cerebellar P-Type Ca2+ Current
نویسندگان
چکیده
منابع مشابه
Developmental activation of calmodulin-dependent facilitation of cerebellar P-type Ca2+ current.
P-type (CaV2.1) Ca2+ channels are a central conduit of neuronal Ca2+ entry, so their Ca2+ feedback regulation promises widespread neurobiological impact. Heterologous expression of recombinant CaV2.1 channels demonstrates that the Ca2+ sensor calmodulin can trigger Ca2+-dependent facilitation (CDF) of channel opening. This facilitation occurs when local Ca2+ influx through individual channels s...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2005
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.2253-05.2005